Preheat oven to 350°F and line a large baking sheet with parchment paper.
Combine flour, sugar, baking powder, pumpkin pie spice, cinnamon, and salt in a large bowl. Then, cut the butter into the bowl and use your hands to toss until the mixture resembles small pebbles.
In a separate bowl, whisk the pumpkin, egg, milk, maple syrup, and vanilla together, then pour the wet ingredients into the dry and stir to combine (see notes below if you're having trouble mixing it).
Flour a baking mat or clean surface, then turn the dough out onto it and form the dough into a large ball. Use your hands to press the ball down into a disc about 7-8 inches in circumference and 1/2 inch thick. Be careful not to make it too thin or the scones won't be the correct texture.
Use a knife to make 4 cuts into the disc to form 8 scones. Transfer the scones to the prepared baking sheet and brush each scone with a little melted butter (optional). Bake the scones for 20 minutes, then remove them from the oven and wait a few minutes before transferring to a cooling rack. Wait at least 10 minutes before adding the glaze.
While the scones are cooling, make the glaze: whisk maple syrup and powdered sugar together. Drizzle glaze over scones and enjoy!